方法低磷血症治疗

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所属分类:疗效
摘要

低磷血症可以是急性或慢性。用磷酸盐耗尽急性低磷血症是在医院环境中,并导致显著共同…

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方法低磷血症治疗

可以低磷血症是急性的或慢性的。用磷酸盐耗尽急性低磷血症是在医院环境中,并导致显著的发病率和死亡率普遍。慢性低磷酸盐血症,常与遗传性或获得性肾磷酸盐浪费病症相关,通常产生在成人异常生长和儿童佝偻病和软骨病。急性低磷血症可能是温和的(磷水平,2-2.5毫克/分升),中度(1-1.9毫克/分升),或重度(<1 mg/dL) and commonly occurs in clinical settings such as refeeding, alcoholism, diabetic ketoacidosis, malnutrition/starvation, and after surgery (particularly after partial hepatectomy) and in the intensive care unit. Phosphate replacement can be given either orally, intravenously, intradialytically, or in total parenteral nutrition solutions. The rate and amount of replacement are empirically determined, and several algorithms are available. Treatment is tailored to symptoms, severity, anticipated duration of illness, and presence of comorbid conditions, such as kidney failure, volume overload, hypo- or hypercalcemia, hypo- or hyperkalemia, and acid-base status. Mild/moderate acute hypophosphatemia usually can be corrected with increased dietary phosphate or oral supplementation, but intravenous replacement generally is needed when significant comorbid conditions or severe hypophosphatemia with phosphate depletion exist. In chronic hypophosphatemia, standard treatment includes oral phosphate supplementation and active vitamin D. Future treatment for specific disorders associated with chronic hypophosphatemia may include 西那卡塞, calcitonin, or dypyrimadole.

索引词

Hypophosphatemiaadenosine三磷酸(ATP)2,3-二磷酸甘油酸(2,3-DPG)成纤维细胞生长因子23(FGF-23)

本来网上公布8月6日,2012

因为该功能编辑自己要求撤换,同行评审和决策过程是处理没有他的参与。的杂志的潜在冲突编辑过程细节在AJKD网站的编辑政策一节中给出。

这是美国政府工作。有对它的使用没有任何限制

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